Regimen inferior to irinotecan for extensive SCLC Amrubicin By Lynda Williams information-om-finasterid.html.

Regimen inferior to irinotecan for extensive SCLC Amrubicin By Lynda Williams, Senior medwireNews Reporter Irinotecan in addition cisplatin remains the gold standard for Japanese patients with extensive small-cell lung cancer tumor , say experts, after amrubicin in addition cisplatin didn’t improve survival within their randomised phase III trial. JAPAN group, led by Miyako Satouchi, from Hyogo Cancer Middle in Akashi, hypothesised that the topoisomerase II inhibitor amrubicin could have equivalent efficacy and much less toxicity compared to the topoisomerase I inhibitor irinotecan. However, the trial was recommended for early publication at the second interim analysis when the point estimate of the hazard ratio for overall survival for IP versus AP was 1 information-om-finasterid.html .41, exceeding the prespecified noninferiority margin of 1 1.31.

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